Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.34 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 4/20 | 0.32 |
| ▸ | METAP1 | P53582 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18735325 | 0.93 | KMT2A (0.41) | KMT2APOLBL3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL18735352 | 0.88 | KMT2A (0.38) | KMT2APOLBL3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL18735061 | 0.86 | KMT2A (0.46) | KMT2APOLBL3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL18735312 | 0.85 | METAP2 (0.36) | KMT2APOLBL3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL18735063 | 0.84 | KMT2A (0.50) | KMT2APOLBL3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL18735313 | 0.83 | METAP2 (0.34) | KMT2APOLBL3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL18734934 | 0.81 | — | — | |
| SCHEMBL18735087 | 0.81 | HDAC2 (0.36) | KMT2APOLBCYP2C9 | |
| SCHEMBL18734801 | 0.81 | HDAC2 (0.36) | KMT2APOLBCYP2C9 | |
| SCHEMBL18735049 | 0.80 | KMT2A (0.43) | KMT2APOLBL3MBTL1CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060400-A1 | PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF DISESASES RELATED TO MITOCHONDRIAL DYSFUNCTIONS | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |