SCHEMBL187377

SCHEMBL187377

CCCC[Si](Cl)(Cl)CCCC

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
THRB P10828 1/20 0.38
ALDH1A1 P00352 3/20 0.36
TP53 P04637 1/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
SLC22A1 O15245 2/20 0.30
SLC22A2 O15244 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704342 0.97 TSHR (0.38) TSHRLMNATDP1THRBALDH1A1
SCHEMBL707007 0.97 TSHR (0.38) TSHRLMNATDP1THRBALDH1A1
SCHEMBL702967 0.97 TSHR (0.38) TSHRLMNATDP1THRBALDH1A1
SCHEMBL2100720 0.94 TSHR (0.35) TSHRLMNATDP1THRBALDH1A1
SCHEMBL11311679 0.91 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL18108347 0.91 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL18108111 0.91 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL133247 0.90 TSHR (0.44) TSHRLMNATDP1THRBALDH1A1
SCHEMBL11313336 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL134147 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12410061-B2 Spray evaporation of a liquid raw material for preparation of silicon dioxide and metal oxides EVONIK OPERATIONS GMBH (DE) 2025-09-09 US claimed
CN-119752386-A Polyurethane sealant for fault indicator and preparation method thereof 广州德汇新材料科技有限公司 2025-04-04 CN claimed
US-20250060673-A1 DEVELOPMENT STRATEGY FOR HIGH-ABSORBING METAL-CONTAINING PHOTORESISTS LAM RES CORP (US) 2025-02-20 US claimed
WO-2024232632-A1 TRANSITION METAL SUPPORTED CATALYST WITH IMPROVED HYDROGENATION ACTIVITY AND USE THEREOF 한양대학교 산학협력단 2024-11-14 WO claimed
CN-118027608-A Controllably degradable epoxy resin-based composite insulating material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-05-14 CN claimed
CN-117903695-A Solid super-smooth surface and construction method and application thereof 青岛理工大学 2024-04-19 CN claimed
EP-3649083-B1 SPRAY EVAPORATION OF A LIQUID RAW MATERIAL FOR PREPARATION OF SILICON DIOXIDE AND METAL OXIDES EVONIK OPERATIONS GMBH (DE) 2023-09-06 EP claimed
WO-2023115023-A1 DEVELOPMENT STRATEGY FOR HIGH-ABSORBING METAL-CONTAINING PHOTORESISTS LAM RESEARCH CORPORATION (US) 2023-06-22 WO claimed
CN-115337267-A Preparation method and application of acid-responsive drug delivery platform based on liposome nano-vesicles 中国科学技术大学 2022-11-15 CN claimed
EP-3649083-A1 SPRAY EVAPORATION OF A LIQUID RAW MATERIAL FOR PREPARATION OF SILICON DIOXIDE AND METAL OXIDES Evonik Operations GmbH (DE) 2020-05-13 EP claimed
US-6811823-B2 CONTACTING SILICA SURFACES WITH DIALKYLDICHLOROSILANES AND TRIALKOXYSILANES THAT ARE FREE OF REACTIVE HYDROCARBON OF ORGANOFUNCTIONAL GROUPS; RUBBER TIRES DOW CORNING CORPORATION 2004-11-02 US claimed
WO-2004024831-A2 HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF DOW CORNING CORPORATION (US) 2004-03-25 WO claimed
US-20040052939-A1 Hydrophobing silica with organosilicon compounds and blends thereof DOW CORNING CORPORATION 2004-03-18 US claimed
US-20030213228-A1 Rocket motor assembly and method for making same ORBITAL ATK, INC. 2003-11-20 US claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed
EP-0502728-B1 Pneumatic tires BRIDGESTONE CORP (JP) 1996-08-14 EP claimed
EP-0502728-A1 Pneumatic tires Bridgestone Corporation (JP) 1992-09-09 EP claimed
US-4780369-A Porous glass membrane tubes JENAER GLASWERK, SCHOTT & GEN. (DE) 1988-10-25 US claimed