Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.32 |
| ▸ | CNR2 | P34972 | 7/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18738841 | 0.96 | CNR1 (0.31) | CNR1CNR2 | |
| SCHEMBL17164357 | 0.88 | CHRNB4 (0.37) | — | |
| SCHEMBL21854579 | 0.87 | MAPT (0.37) | — | |
| SCHEMBL17164367 | 0.84 | S1PR4 (0.38) | — | |
| SCHEMBL18458344 | 0.79 | TP53 (0.48) | TP53ALOX15POLB | |
| SCHEMBL18458781 | 0.74 | TP53 (0.45) | TP53ALOX15POLB | |
| SCHEMBL20522004 | 0.74 | MAPT (0.39) | — | |
| SCHEMBL28108700 | 0.74 | PPARA (0.42) | CNR1CNR2 | |
| SCHEMBL18738729 | 0.73 | HSP90AB1 (0.37) | — | |
| SCHEMBL20521493 | 0.73 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129387-B1 | NOVEL MACROCYCLIC COMPOUNDS | Bayer Pharma AG (DE) | 2019-06-26 | — | — | EP | disclosed |
| WO-2017060322-A2 | PTEFB-INHIBITOR-ADC | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | WO | disclosed |