SCHEMBL18740293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18740019	0.92	GAA (0.38)	GAANPC1PKMGABRPGABRD
	SCHEMBL21474421	0.88	KDM4E (0.38)	GAANPC1PKMGABRPGABRD
	SCHEMBL18740040	0.83	PLAT (0.33)	GAANPC1PKMGABRPGABRD
	SCHEMBL18740230	0.80	GAA (0.34)	GAANPC1PKMGABRPGABRD
	SCHEMBL4625215	0.79	NPC1 (0.48)	GAANPC1PKMGABRPGABRD
	SCHEMBL18740061	0.75	LMNA (0.35)	GAAGABRPGABRDGABRA1GABRB1
	SCHEMBL28240689	0.73	SCN5A (0.36)	GAAALDH1A1HTTSCN5ASCN9A
	SCHEMBL22286228	0.71	MAPK1 (0.46)	GAANPC1PKMGABRPGABRD
	SCHEMBL20551457	0.71	MAPK1 (0.41)	GAANPC1PKMGABRPGABRD
	SCHEMBL10572038	0.68	HPGD (0.67)	NPC1PKMGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.