SCHEMBL18740303

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18740167	0.93	HDAC1 (0.42)	KDM4EALDH1A1HIF1AEPAS1SIGMAR1
	SCHEMBL18739995	0.91	GRIA2 (0.40)	SIGMAR1KCNH2CYP1A2CYP2C9GRIA2
	SCHEMBL18740131	0.88	PTGER4 (0.46)	KDM4EALDH1A1SIGMAR1FAAHKCNH2
	SCHEMBL18740168	0.87	KDM4E (0.41)	KDM4EALDH1A1HIF1AEPAS1HRH3
	SCHEMBL18740150	0.85	TDP1 (0.42)	KDM4EALDH1A1SIGMAR1FAAHCYP1A2
	SCHEMBL18740044	0.84	HPGD (0.39)	KDM4EALDH1A1SIGMAR1KCNH2CYP1A2
	SCHEMBL18740177	0.84	MEN1 (0.43)	ALDH1A1HDAC1
	SCHEMBL18740161	0.83	SMN1; SMN2 (0.38)	KDM4EALDH1A1CYP1A2CYP2C9GRIA2
	SCHEMBL18740316	0.83	LMNA (0.44)	KDM4EALDH1A1LMNA
	SCHEMBL18740042	0.82	PTGER4 (0.58)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.