SCHEMBL1874073

SCHEMBL1874073

CCCCCCCCCC(C)(C)[S+]([O-])CC(O)COc1c(C(C)c2cc(C(C)(C)C)cc(C(C)(C)C)c2O)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
NR5A2 O00482 1/20 0.31
NR5A1 Q13285 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12633334 0.79 CYP3A4 (0.48) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL12633331 0.74 CYP3A4 (0.39) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL6394818 0.70 CYP1A2 (0.45) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL11797037 0.70 CYP1A2 (0.45) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL1876833 0.67 GGPS1 (0.33)
SCHEMBL27322 0.67 CYP1A2 (0.57) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL30962428 0.67 CYP1A2 (0.57) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL14524739 0.66 SMN1; SMN2 (0.42) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
Phosphoric Acid SCHEMBL7731640 0.66 CYP3A4 (0.48) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL6608332 0.66 RXRA (0.45) CYP1A2CYP3A4CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947831-B2 Sulfoxides or sulfones grafted onto polymers BASF SE Ludwigshafen (DE) 2011-05-24 US disclosed
US-20070015870-A1 Sulfoxides or sulfones grafted onto polymers CIBA CORPORATION 2007-01-18 US disclosed
US-7160955-B2 Sulfoxides or sulfones grafted onto polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-09 US disclosed
US-20040152836-A1 Sulfoxides or sulfones grafted onto polymers CIBA SPECIALTY CHEMICALS CORP. 2004-08-05 US disclosed
EP-1373196-A2 SULFOXIDES OR SULFONES GRAFTED ONTO POLYMERS Ciba SC Holding AG (CH) 2004-01-02 EP disclosed
WO-2002081432-A2 SULFOXIDES OR SULFONES GRAFTED ONTO POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-17 WO disclosed