SCHEMBL18741007

SCHEMBL18741007

CCCc1ccc(-c2cc[c]s2)s1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP2E1 P05181 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2B6 P20813 1/20 0.33
CYP2C19 P33261 1/20 0.33
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1286042 0.90 MAPT (0.36)
SCHEMBL18741093 0.88 MAPT (0.33)
SCHEMBL1285999 0.87 POLB (0.33) CYP3A4
SCHEMBL1285970 0.87 POLB (0.33) CYP3A4
SCHEMBL18740927 0.85 MEN1 (0.33) CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6
SCHEMBL5575477 0.76
SCHEMBL131435 0.74
SCHEMBL12830678 0.73 MAPT (0.41) CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6
SCHEMBL12830677 0.73 MAPT (0.41) CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6
SCHEMBL18568777 0.73 CYP2E1 (0.43) CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017064243-A1 USE OF PHTHALOCYANINE COMPOUNDS WITH ARYL OR HETARYL SUBSTITUENTS IN GAS SENSORS BASF SE (DE) 2017-04-20 WO disclosed