Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | KRAS | P01116 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18741311 | 1.00 | MAPT (0.71) | MAPTNPSR1TNFRSF1AKMT2AMEN1 | |
| SCHEMBL16263995 | 0.89 | TNFRSF1A (0.67) | MAPTNPSR1TNFRSF1AKMT2AMEN1 | |
| SCHEMBL15732330 | 0.89 | MAPT (0.80) | MAPTNPSR1TNFRSF1AKMT2AMEN1 | |
| SCHEMBL8248887 | 0.89 | MAPT (0.70) | MAPTNPSR1TNFRSF1AKMT2AMEN1 | |
| SCHEMBL15732329 | 0.89 | MAPT (0.80) | MAPTNPSR1TNFRSF1AKMT2AMEN1 | |
| SCHEMBL1201269 | 0.85 | ABCB1 (0.67) | MAPTNPSR1TNFRSF1AKMT2AMEN1 | |
| SCHEMBL27860091 | 0.83 | TNFRSF1A (0.70) | MAPTNPSR1TNFRSF1AKMT2AMEN1 | |
| SCHEMBL17583539 | 0.82 | ABCB1 (0.81) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL17583538 | 0.82 | ABCB1 (0.81) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL25203552 | 0.82 | MAPT (0.86) | MAPTNPSR1TNFRSF1AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017065515-A1 | COMPOSITION FOR PREVENTING OR TREATING GYNECOLOGICAL CANCERS AND MENOPAUSAL SYMPTOMS CONTAINING FLEMINGIA STROBILIFERA EXTRACT OR COMPOUND ISOLATED THEREFROM AS ACTIVE INGREDIENT | 숙명여자대학교 산학협력단 | 2017-04-20 | — | — | WO | disclosed |