Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.70 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647781 | 0.89 | MCL1 (0.81) | TNFRSF1AKCNA3MCL1MAPTMEN1 | |
| SCHEMBL14315253 | 0.87 | CYP1A1 (0.72) | TNFRSF1AKCNA3MCL1MAPTMEN1 | |
| SCHEMBL31436378 | 0.87 | CYP1A1 (0.72) | TNFRSF1AKCNA3MCL1MAPTMEN1 | |
| SCHEMBL1882355 | 0.87 | CYP1A1 (0.72) | TNFRSF1AKCNA3MCL1MAPTMEN1 | |
| SCHEMBL30736480 | 0.87 | CYP1A1 (0.72) | TNFRSF1AKCNA3MCL1MAPTMEN1 | |
| SCHEMBL18741310 | 0.83 | MAPT (0.71) | TNFRSF1AKCNA3MAPTMEN1NPC1 | |
| SCHEMBL18741311 | 0.83 | MAPT (0.71) | TNFRSF1AKCNA3MAPTMEN1NPC1 | |
| SCHEMBL12484518 | 0.82 | TNFRSF1A (1.00) | TNFRSF1AABCG2ABCB1TUBB1 | |
| SCHEMBL12484514 | 0.82 | TNFRSF1A (1.00) | TNFRSF1AABCG2ABCB1TUBB1 | |
| SCHEMBL31233236 | 0.81 | CYP1A2 (0.76) | TNFRSF1AKCNA3MAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102267888-A | Chalcone derivative as well as preparation method and application thereof used as inducer in inducing apoptosis of tumor cells | — | 2011-12-07 | — | — | CN | claimed |
| CN-102267888-A | Chalcone derivative as well as preparation method and application thereof used as inducer in inducing apoptosis of tumor cells | — | 2011-12-07 | — | — | CN | disclosed |