Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 6/20 | 0.41 |
| ▸ | FUT6 | P51993 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14143192 | 0.93 | HINT1 (0.46) | HINT1TAS1R3TAS1R1NT5EADORA3 | |
| SCHEMBL17232119 | 0.92 | HINT1 (0.49) | HINT1TAS1R3TAS1R1NT5EADORA3 | |
| SCHEMBL10819901 | 0.90 | HINT1 (0.46) | HINT1TAS1R3TAS1R1NT5EADORA3 | |
| SCHEMBL13522446 | 0.90 | HINT1 (0.46) | HINT1TAS1R3TAS1R1NT5EADORA3 | |
| SCHEMBL13523353 | 0.90 | HINT1 (0.46) | HINT1TAS1R3TAS1R1NT5EADORA3 | |
| SCHEMBL13522430 | 0.90 | HINT1 (0.46) | HINT1TAS1R3TAS1R1NT5EADORA3 | |
| SCHEMBL10819885 | 0.90 | HINT1 (0.46) | HINT1TAS1R3TAS1R1NT5EADORA3 | |
| SCHEMBL15468729 | 0.90 | HINT1 (0.46) | HINT1TAS1R3TAS1R1NT5EADORA3 | |
| SCHEMBL3132403 | 0.90 | HINT1 (0.45) | HINT1TAS1R3TAS1R1NT5EADORA3 | |
| SCHEMBL16350180 | 0.90 | HINT1 (0.45) | HINT1TAS1R3TAS1R1NT5EADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624249-B2 | Nucleoside kinase bypass compositions and methods | MERCK SHARP & DOHME CORP. (US) | 2017-04-18 | — | — | US | disclosed |