Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18744150 | 1.00 | LMNA (0.44) | LMNAHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL18744145 | 0.99 | LMNA (0.46) | LMNAHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL18744149 | 0.97 | LMNA (0.44) | LMNAHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL15036507 | 0.92 | HSD17B10 (0.41) | LMNAHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL15036505 | 0.88 | HSD17B10 (0.43) | KMT2ACA1CA2CA7CA14 | |
| SCHEMBL15036517 | 0.88 | HSD17B10 (0.43) | KMT2ACA1CA2CA7CA14 | |
| SCHEMBL15036512 | 0.88 | HSD17B10 (0.43) | KMT2ACA1CA2CA7CA14 | |
| SCHEMBL15042619 | 0.88 | HSD17B10 (0.43) | KMT2ACA1CA2CA7CA14 | |
| SCHEMBL15036506 | 0.83 | HSD17B10 (0.45) | LMNAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL12031710 | 0.81 | CNR1 (0.46) | LMNAHDAC8HDAC3HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9623345-B2 | Phase selective gelation with alkylated aromatic acid compounds | XEROX CORPORATION (US) | 2017-04-18 | — | — | US | disclosed |