SCHEMBL187445

SCHEMBL187445

O=C1C=CC(=O)N1c1cccc2c1C1CCC2c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.50
MGLL Q99685 15/20 0.43
FAAH O00519 5/20 0.40
ALDH1A1 P00352 2/20 0.37
HSP90AA1 P07900 2/20 0.37
PKM P14618 2/20 0.37
ATM Q13315 2/20 0.37
CCR6 P51684 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HTT P42858 1/20 0.33
EEF2K O00418 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9719942 0.74 TLR9 (0.59) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL4235441 0.72 TLR9 (0.43) TLR9MGLLFAAH
SCHEMBL9495394 0.70 TLR9 (0.53) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL29377102 0.70 TLR9 (1.00) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL121404 0.70 TLR9 (1.00) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL28883386 0.69 TLR9 (0.47) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL5970019 0.68 TLR9 (0.50) TLR9MGLL
SCHEMBL4952572 0.67 HTR2A (0.41)
SCHEMBL31236391 0.67 HTR2A (0.41)
SCHEMBL3755356 0.67 HTR2A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2402136-B1 POWDER SLUSH MOLDING MACHINE AND POWDER SLUSH MOLDING METHOD FAURECIA INNENRAUM SYS GMBH (DE) 2016-05-18 EP disclosed
US-8814550-B2 Powder slush molding machine and powder slush molding method NAKATA COATING CO., LTD. (JP) 2014-08-26 US disclosed
EP-2402136-A1 POWDER SLUSH MOLDING MACHINE AND POWDER SLUSH MOLDING METHOD Nakata Coating Co., Ltd. (JP) 2012-01-04 EP disclosed
US-20110316184-A1 Powder Slush Molding Machine and Powder Slush Molding Method NAKATA COATING CO., LTD. (JP) 2011-12-29 US disclosed
EP-0359464-B1 Heat resistant polyvinyl chloride copolymer and preparation process of the copolymer MITSUI TOATSU CHEMICALS (JP) 1994-07-20 EP disclosed
US-5166271-A N-substituted maleimide with vinyl chloride graft polymerized MITSUI TOATSU CHEMICALS, INC. (JP) 1992-11-24 US disclosed
US-5089575-A Suspension polymerization in aqueous medium containing partially saponified polyvinyl alcohol and water soluble cellulose SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-02-18 US disclosed
EP-0359464-A2 Heat resistant polyvinyl chloride copolymer and preparation process of the copolymer MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-03-21 EP disclosed