Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482601 | 1.00 | HTR2A (0.41) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4952572 | 1.00 | HTR2A (0.41) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31236391 | 1.00 | HTR2A (0.41) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11114224 | 0.87 | HTR2A (0.39) | HTR2A | |
| SCHEMBL11253742 | 0.79 | HTR2A (0.52) | HTR2A | |
| SCHEMBL11740479 | 0.78 | HTR2A (0.42) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8889940 | 0.76 | HTR1A (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11738636 | 0.76 | MEN1 (0.45) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29789885 | 0.76 | SLC6A2 (0.37) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29394336 | 0.76 | SLC6A2 (0.37) | HTR2ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691998-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-04-08 | — | — | US | claimed |
| US-20130190508-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-07-25 | — | — | US | claimed |
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-18 | — | — | US | claimed |
| WO-2008101197-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-08-21 | — | — | WO | claimed |
| US-11912999-B2 | Aptamer conjugates with N-heterocyclic carbene metal complexes for targeted drug delivery | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-8691998-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-04-08 | — | — | US | disclosed |
| US-20130190508-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-8455661-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912999-B2 | Aptamer conjugates with N-heterocyclic carbene metal complexes for targeted drug delivery | NTPCR, NDC1, PAICS | HTR2A 1565/4885SLC6A2 1419/4885SLC6A4 1624/4885 |
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | NDC1, NBAS, NIT2 | HTR2A 418/4885SLC6A2 2695/4885SLC6A4 2537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.