Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 17/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.50 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | ROS1 | P08922 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31570692 | 0.92 | ADK (0.57) | ADKSLC29A1DOT1LNPC1GALR3 | |
| SCHEMBL3290600 | 0.87 | ADK (0.68) | ADKSLC29A1DOT1LNPC1GALR3 | |
| SCHEMBL31526094 | 0.86 | ADK (0.56) | ADKSLC29A1RAB9AHASPIN | |
| SCHEMBL31570708 | 0.86 | ADK (0.56) | ADKSLC29A1RAB9AHASPIN | |
| SCHEMBL16978213 | 0.84 | ADK (0.61) | ADKSLC29A1HASPIN | |
| SCHEMBL18744635 | 0.84 | ADK (0.56) | ADKSLC29A1RAB9AHASPIN | |
| SCHEMBL19271868 | 0.84 | ADK (0.61) | ADKSLC29A1HASPIN | |
| SCHEMBL16968466 | 0.84 | ADK (0.56) | ADKSLC29A1RAB9AHASPIN | |
| Iodotubercidin SCHEMBL2786488 | 0.83 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL12505209 | 0.83 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240584-A1 | NOVEL 7-DEAZAPURINE NUCLEOSIDES FOR THERAPEUTIC USES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR,V.V.I. (CZ) | 2017-08-24 | — | — | US | disclosed |
| US-9624257-B2 | 7-deazapurine nucleosides for therapeutic uses | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ASCR, V.V.I. (CZ) | 2017-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240584-A1 | NOVEL 7-DEAZAPURINE NUCLEOSIDES FOR THERAPEUTIC USES | TPMT, TYMP, ENTPD5 | ADK 272/4885SLC29A1 5/4885DOT1L 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.