Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255421 | 0.80 | EPHX1 (0.59) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL28895020 | 0.78 | EPHX1 (0.57) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL1802727 | 0.77 | EPHX1 (0.55) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL11007528 | 0.75 | EPHX1 (0.53) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL21730427 | 0.74 | EPHX1 (0.52) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL19716609 | 0.72 | EPHX1 (0.50) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL22233273 | 0.72 | EPHX1 (0.50) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL11627259 | 0.72 | EPHX1 (0.50) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL7449252 | 0.72 | EPHX1 (0.49) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL19086797 | 0.72 | EPHX1 (0.59) | EPHX1POLBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9623014-B2 | β-lactamase inhibitor compounds | ENTASIS THERAPEUTICS LIMITED (GB) | 2017-04-18 | — | — | US | disclosed |