Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.47 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15472278 | 0.87 | MAOB (0.58) | ACACAMEN1KMT2AMRGPRX4RXRA | |
| SCHEMBL15472291 | 0.86 | GPR132 (0.51) | SMN1; SMN2MAPK1MRGPRX4CYP11B1 | |
| SCHEMBL18745406 | 0.85 | MAOB (0.52) | ACACAMEN1MAPK1KMT2AMRGPRX4 | |
| SCHEMBL15472344 | 0.85 | MAOB (0.56) | ACACASMN1; SMN2HTTMRGPRX4RXRA | |
| SCHEMBL15472276 | 0.85 | MAOB (0.60) | ACACAMRGPRX4RXRARXRBMAOB | |
| SCHEMBL15474272 | 0.85 | MAOB (0.59) | NOS3NOS1NOS2CYP27B1CYP24A1 | |
| SCHEMBL15474297 | 0.84 | MAOB (0.61) | ACACAMRGPRX4RXRARXRBMAOB | |
| SCHEMBL15472428 | 0.83 | MAOB (0.54) | ACACAMAOBFFAR1 | |
| SCHEMBL18745392 | 0.81 | MAOB (0.54) | MRGPRX4RXRARXRBMAOBFFAR1 | |
| SCHEMBL18745423 | 0.81 | MAOB (0.57) | SMN1; SMN2MRGPRX4MAOBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624239-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-04-18 | — | — | US | disclosed |