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GPR132

Probable G-protein coupled receptor 132 · Q9UNW8 · GPR132 on Sugi Atlas →

13,701 patent compounds predicted against GPR132, 9,057 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1123378 SCHEMBL1123378 0.57 16/20
SCHEMBL1123379 SCHEMBL1123379 0.95 15/20
SCHEMBL1123392 SCHEMBL1123392 0.78 15/20
SCHEMBL1123407 SCHEMBL1123407 0.77 15/20
SCHEMBL1071435 SCHEMBL1071435 0.54 15/20
SCHEMBL1070049 SCHEMBL1070049 0.52 15/20
SCHEMBL1070071 SCHEMBL1070071 0.51 15/20
SCHEMBL1123130 SCHEMBL1123130 0.80 14/20
SCHEMBL1122704 SCHEMBL1122704 0.68 14/20
SCHEMBL1123431 SCHEMBL1123431 0.61 14/20
SCHEMBL1123228 SCHEMBL1123228 0.60 14/20
SCHEMBL1122810 SCHEMBL1122810 0.93 13/20
SCHEMBL1123644 SCHEMBL1123644 0.93 13/20
SCHEMBL1123646 SCHEMBL1123646 0.93 13/20
SCHEMBL1122680 SCHEMBL1122680 0.89 13/20
SCHEMBL1122807 SCHEMBL1122807 0.82 13/20
SCHEMBL1123119 SCHEMBL1123119 0.77 13/20
SCHEMBL1122855 SCHEMBL1122855 0.74 13/20
SCHEMBL1122856 SCHEMBL1122856 0.74 13/20
SCHEMBL1122977 SCHEMBL1122977 0.68 13/20

Clinical trials — most relevant to GPR132 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell. PHASE4UNKNOWN
Beta-arrestins and Response to Venlafaxine in Major Depressive Disorder (MDD) (DEPARRESTCLIN) PHASE4COMPLETED
Medication, Weight Gain and GI Hormones PHASE4COMPLETED
Effects of Liraglutide in Young Adults With Type 2 DIAbetes (LYDIA) PHASE3COMPLETED
A Series of Pilot Studies to Evaluate the haemoDynamic and mEtabolic Effects oF apelIn aNd rElaxin PHASE2UNKNOWN
Meclizine for Hepatocellular Carcinoma PHASE1COMPLETED
The Role of Endocannabinoids in Insulin Production and Action PHASE1COMPLETED
Excitatory Amino Acids and Activated Microglia After Traumatic Brain Injury: a (R)-[11C]PK11195 PET Study PHASE1UNKNOWN
Assessment of [11C]ER176 to Image Translocator Protein in Brain and Whole Body of Healthy People EARLY_PHASE1COMPLETED
A Positional Cloning Study on Schizophrenia nanCOMPLETED
Oat Bran and Plasma Lipid and Fecal Bacteria in Coronary Artery Disease Patients nanCOMPLETED
Effect of Dietary Oils as G-protein-coupled Receptor Agonists on Glucose Tolerance nanUNKNOWN
Genetic Influences of Albuterol Response In Children With Bronchiolitis nanCOMPLETED
Brain Receptors in Sympathetic Nervous System Regulation nanCOMPLETED
Selective Activation of the Adrenomedullin Receptors in Migraine nanNOT_YET_RECRUITING
Acute Asthma Responsiveness and B2 Adrenergic Receptors Polymorphisms nanCOMPLETED
Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome nanACTIVE_NOT_RECRUITING
Longitudinal Analysis of Amylin Levels in Migraine Patients Undergoing an Anti- CGRP/CGRPr Treatment nanNOT_YET_RECRUITING
Effects of an Amino Acid-Based hGH Secretagogue on Triiodythyronine nanCOMPLETED
Metabotropic Receptors For Glutamate Type 3 In Parkinson's nanUNKNOWN
The Impact of Pharmacological and Electric Modulation of NMDA Pathway on the Cognitive Flexibility and Volitional Movement Preparation in Patients With Parkinson's Disease nanCOMPLETED
The Application of 68Ga-Pentixafor Alongside 68Ga-FAPI-04 PET/MR for Assessing Primary Aldosteronism. nanNOT_YET_RECRUITING
Family Resilience Initiative Research Program nanUNKNOWN
Pharmacogenetics and Cardiovascular Events nanCOMPLETED
Forced Oscillometry in Infants With Bronchopulmonary Dysplasia nanRECRUITING
GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures nanCOMPLETED
FFAR Agonist on Incretins, Insulin, Lipids and Inflammation nanCOMPLETED
Adrenocorticotropic Hormone (ACTH) Stimulation and G Protein nanCOMPLETED
Effects of Probiotics on Gut Microbiota, Endocannabinoid and Immune Activation and Symptoms of Fatigue in Dancers nanCOMPLETED
The Role of Autoantibodies Against G-protein Coupled Receptors in Obesity nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a GPR132 binder may also engage these)

ProteinNameSimilarity
Q9Z282 — 1.000 Q9Z282 →
Q8BUD0 — 0.992 Q8BUD0 →
E7FEL0 — 0.990 E7FEL0 →
P31392 — 0.987 P31392 →
GPR4 G-prodeshotein coupled receptor 4 0.987 landscape →
Q4KLH9 — 0.986 Q4KLH9 →
Q8C131 — 0.986 Q8C131 →
Q9XSD4 — 0.986 Q9XSD4 →
O46685 — 0.986 O46685 →
A0A4W3GG95 — 0.985 A0A4W3GG95 →
Q61038 — 0.985 Q61038 →
GPR68 G-protein coupled receptor 68 0.985 landscape →
Q1JQB3 — 0.984 Q1JQB3 →
P43142 — 0.983 P43142 →
HCAR2 Hydroxycarboxylic acid receptor 2 0.982 landscape →
P21556 — 0.982 P21556 →
Q80Z39 — 0.981 Q80Z39 →
PTAFR Platelet-activating factor receptor 0.981 landscape →
P2RY10 Putative P2Y purinoceptor 10 0.981 landscape →
HCAR1 Hydroxycarboxylic acid receptor 1 0.980 landscape →
Q9GK76 — 0.980 Q9GK76 →
Q3U6B2 — 0.980 Q3U6B2 →
Q8BFQ3 — 0.980 Q8BFQ3 →
Q3U507 — 0.980 Q3U507 →
GPR174 Probable G-protein coupled receptor 174 0.979 landscape →
D4A7K7 — 0.979 D4A7K7 →
B0UXR0 — 0.979 B0UXR0 →
P46002 — 0.979 P46002 →
Q9TTY5 — 0.978 Q9TTY5 →
P50132 — 0.978 P50132 →