Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003 | 0.88 | LPAR1 (0.54) | LPAR1LPAR3MAPTKDM4EABCC3 | |
| SCHEMBL2761525 | 0.84 | LPAR1 (0.57) | LPAR1LPAR3MAPTKDM4EABCC3 | |
| SCHEMBL11389 | 0.81 | NPC1 (0.51) | LPAR1LPAR3MAPTKDM4EABCC3 | |
| SCHEMBL2761399 | 0.81 | LPAR1 (0.54) | LPAR1LPAR3MAPTKDM4EABCC3 | |
| SCHEMBL1345 | 0.80 | LPAR1 (0.53) | LPAR1LPAR3MAPTKDM4EABCC3 | |
| SCHEMBL2761476 | 0.80 | LPAR1 (0.65) | LPAR1LPAR3MAPTKDM4EABCC3 | |
| SCHEMBL6434 | 0.79 | LPAR1 (0.49) | LPAR1LPAR3MAPTKDM4EABCC3 | |
| SCHEMBL18597709 | 0.79 | LPAR1 (0.40) | LPAR1LPAR3MAPTKDM4EABCC3 | |
| SCHEMBL2761269 | 0.78 | LPAR1 (0.63) | LPAR1LPAR3MAPTKDM4EABCC3 | |
| SCHEMBL12973654 | 0.78 | LPAR1 (0.63) | LPAR1LPAR3MAPTKDM4EABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624182-B2 | Compounds as lysophosphatidic acid receptor antagonists | AMIRA PHARMACEUTICALS, INC. (US) | 2017-04-18 | — | — | US | disclosed |