Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900680 | 0.86 | MAPK1 (0.52) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30816026 | 0.80 | OPRK1 (0.48) | ATRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL473981 | 0.80 | OPRK1 (0.48) | ATRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL3520084 | 0.78 | MAPK1 (0.47) | ATRMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL31368194 | 0.78 | CA12 (0.49) | ATRMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL26660324 | 0.78 | CA12 (0.49) | ATRMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL3732128 | 0.78 | ATM (0.47) | ATRMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL2582436 | 0.77 | OPRK1 (0.46) | ATRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8272694 | 0.77 | TSHR (0.41) | ATRMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL733159 | 0.77 | OPRK1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624215-B2 | Amine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2017-04-18 | — | — | US | disclosed |