Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 17/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17195437 | 0.79 | DGAT1 (0.49) | DGAT1 | |
| SCHEMBL15742518 | 0.78 | DGAT1 (0.47) | DGAT1AOC3 | |
| SCHEMBL14061891 | 0.78 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL14061631 | 0.76 | SMN1; SMN2 (0.49) | DGAT1AOC3 | |
| SCHEMBL14061811 | 0.76 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL19443193 | 0.75 | DGAT1 (0.43) | DGAT1MAPK14 | |
| SCHEMBL15743107 | 0.75 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL14061904 | 0.74 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL14062380 | 0.72 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL14061937 | 0.71 | DGAT1 (0.53) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624174-B2 | Compounds as diacylglycerol acyltransferase inhibitors | GLAXOSMITHKLINE LLC (US) | 2017-04-18 | — | — | US | disclosed |