SCHEMBL18746465

SCHEMBL18746465

COP(=O)(OCCN(C)C)OCC(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14849209 0.91 CYP3A4 (0.35) PIK3CDGAAMEN1KMT2A
SCHEMBL18746538 0.88 CYP3A4 (0.33) PIK3CDGAAMEN1KMT2A
SCHEMBL15263479 0.87 CHRM2 (0.37)
SCHEMBL15150921 0.82 CHRM2 (0.37)
SCHEMBL3818106 0.82 ALDH1A1 (0.35) GAAMEN1KMT2A
SCHEMBL2625109 0.79 CYP3A4 (0.40) MEN1KMT2A
SCHEMBL2231833 0.78 ALDH1A1 (0.35) GAAMEN1KMT2A
SCHEMBL17832967 0.76 CYP3A4 (0.41)
SCHEMBL14849208 0.76 MVD (0.39) PIK3CDGAAMEN1KMT2A
SCHEMBL3029332 0.76 CYP3A4 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2575764-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2017-04-19 EP disclosed