SCHEMBL18748645

SCHEMBL18748645

c1ccc(-c2ccc(-c3ccc4c(c3)c3c5ccccc5c5c6ccccc6sc5c3n4-c3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.36
TNKS O95271 2/20 0.33
TNKS2 Q9H2K2 2/20 0.33
TP53 P04637 2/20 0.33
NR3C1 P04150 1/20 0.32
RXFP1 Q9HBX9 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSPO P30536 1/20 0.32
PIM3 Q86V86 2/20 0.31
PTPN1 P18031 2/20 0.31
ALOX5 P09917 1/20 0.31
MAPT P10636 3/20 0.31
PIM1 P11309 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
PTPRC P08575 1/20 0.30
PTPRF P10586 1/20 0.30
PTPRA P18433 1/20 0.30
PTPRB P23467 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18748681 1.00 LIMK1 (0.36) LIMK1TNKSTNKS2TP53NR3C1
SCHEMBL15126615 1.00 LIMK1 (0.36) LIMK1TNKSTNKS2TP53NR3C1
SCHEMBL18748694 1.00 LIMK1 (0.36) LIMK1TNKSTNKS2TP53NR3C1
SCHEMBL15126834 0.97 LIMK1 (0.36) LIMK1TNKSTNKS2TP53RXFP1
SCHEMBL18748623 0.97 LIMK1 (0.36) LIMK1TNKSTNKS2TP53RXFP1
SCHEMBL18748685 0.96 ATM (0.36) LIMK1TNKSTNKS2TP53RXFP1
SCHEMBL15138773 0.95 LIMK1 (0.39) LIMK1TNKSTNKS2TP53NR3C1
SCHEMBL18748693 0.95 ATM (0.37) LIMK1TNKSTNKS2TP53RXFP1
SCHEMBL18748696 0.94 ALOX5 (0.34) LIMK1TNKSTNKS2TP53RXFP1
SCHEMBL15126444 0.93 LIMK1 (0.35) LIMK1TNKSTNKS2NR3C1PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170110669-A1 ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE HAVING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-20 US disclosed
US-20170110669-A1 ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE HAVING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-20 US disclosed