Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18748973 | 0.90 | SMN1; SMN2 (0.58) | MAPTMRGPRX4HPGDALDH1A1MEN1 | |
| SCHEMBL18749778 | 0.89 | HPGD (0.54) | MAPTMRGPRX4HPGDALDH1A1CYP1A2 | |
| SCHEMBL18749745 | 0.89 | HPGD (0.54) | MAPTMRGPRX4HPGDMEN1KMT2A | |
| SCHEMBL20425116 | 0.89 | LMNA (0.58) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18748809 | 0.88 | KMT2A (0.50) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL18748940 | 0.88 | MAPT (0.45) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8174651 | 0.88 | KMT2A (0.51) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL18515397 | 0.88 | FFAR4 (0.48) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL18748986 | 0.88 | SMN1; SMN2 (0.46) | MAPTMRGPRX4HPGDALDH1A1MEN1 | |
| SCHEMBL18749277 | 0.87 | MAPT (0.47) | MAPTMRGPRX4HPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040768-B2 | Carbamate compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-08-07 | — | — | US | disclosed |
| US-9907307-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20180014539-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-18 | — | — | US | disclosed |
| US-20180002294-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-04 | — | — | US | disclosed |
| US-20180002291-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-04 | — | — | US | disclosed |
| US-20170360044-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20170342032-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-30 | — | — | US | disclosed |
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040768-B2 | Carbamate compound and use thereof | C9, C5, C1S | MAPT 3358/4885MRGPRX4 814/4885HPGD 4389/4885 |
| US-20180014539-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | MAPT 3347/4885MRGPRX4 763/4885HPGD 4443/4885 |
| US-20170360044-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | MAPT 3184/4885MRGPRX4 620/4885HPGD 4194/4885 |
| US-20170342032-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | MAPT 3169/4885MRGPRX4 554/4885HPGD 4207/4885 |
| US-20180002291-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | MAPT 3308/4885MRGPRX4 703/4885HPGD 4441/4885 |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-0 | MAPT 3329/4885MRGPRX4 959/4885HPGD 4800/4885 |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-10 | MAPT 2998/4885MRGPRX4 778/4885HPGD 4398/4885 |
| US-20180002294-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | MAPT 3358/4885MRGPRX4 814/4885HPGD 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.