Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18515235 | 0.91 | HDAC8 (0.41) | HDAC8FFAR1FFAR4MRGPRX4PTGDR2 | |
| SCHEMBL18749866 | 0.88 | MAPT (0.46) | FFAR1FFAR4PTGDR2ANO1CD274 | |
| SCHEMBL18749647 | 0.86 | SLC22A12 (0.43) | HDAC8FFAR1FFAR4MRGPRX4ANO1 | |
| SCHEMBL18749859 | 0.86 | KMT2A (0.41) | HDAC8FFAR1FFAR4MRGPRX4ANO1 | |
| SCHEMBL18749696 | 0.86 | MRGPRX4 (0.50) | HDAC8FFAR1FFAR4MRGPRX4CD274 | |
| SCHEMBL18749633 | 0.86 | MRGPRX4 (0.38) | HDAC8FFAR1FFAR4MRGPRX4ANO1 | |
| SCHEMBL18749543 | 0.86 | LMNA (0.44) | HDAC8FFAR1FFAR4MRGPRX4PTGDR2 | |
| SCHEMBL18749980 | 0.85 | MRGPRX4 (0.40) | HDAC8FFAR1FFAR4MRGPRX4ANO1 | |
| SCHEMBL18749695 | 0.85 | MCL1 (0.43) | MRGPRX4PTGDR2CD274TP53HTT | |
| SCHEMBL18749701 | 0.84 | MRGPRX4 (0.38) | HDAC8MRGPRX4ANO1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9907307-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-06 | — | — | US | disclosed |
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-0 | HDAC8 1071/4885FFAR1 3450/4885FFAR4 4194/4885 |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-10 | HDAC8 1611/4885FFAR1 3287/4885FFAR4 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.