Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1874300 | 0.92 | — | — | |
| SCHEMBL2191422 | 0.85 | NR1I2 (0.36) | — | |
| SCHEMBL1127372 | 0.82 | KMO (0.32) | — | |
| SCHEMBL12230885 | 0.80 | MAPK14 (0.34) | MAPK1 | |
| SCHEMBL12669269 | 0.80 | MEN1 (0.33) | — | |
| SCHEMBL1876861 | 0.78 | ALOX5AP (0.33) | — | |
| SCHEMBL1127552 | 0.76 | KCNH2 (0.37) | — | |
| SCHEMBL1875851 | 0.75 | MEN1 (0.32) | — | |
| SCHEMBL12669712 | 0.75 | MEN1 (0.36) | MAPK1 | |
| SCHEMBL12230897 | 0.75 | PDCD1 (0.33) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011059610-A1 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-05-19 | — | — | WO | disclosed |