Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 7/20 | 0.44 |
| ▸ | TTK | P33981 | 7/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10218689 | 0.84 | PIM1 (0.45) | PIM1TTKPIM2 | |
| SCHEMBL11023707 | 0.82 | PIM1 (0.52) | PIM1TTKPIM2 | |
| SCHEMBL9937049 | 0.81 | PIM1 (0.52) | PIM1TTKPIM2 | |
| Hydrochloric Acid SCHEMBL9937475 | 0.80 | PIM1 (0.51) | PIM1TTKPIM2 | |
| SCHEMBL9937233 | 0.78 | PIM1 (0.48) | PIM1TTKPIM2 | |
| SCHEMBL9937579 | 0.77 | PIM1 (0.49) | PIM1TTKPIM2 | |
| SCHEMBL10218688 | 0.73 | PIM1 (0.40) | PIM1TTKPIM2 | |
| SCHEMBL9937660 | 0.70 | PIM1 (0.60) | PIM1TTKPIM2 | |
| Hydrochloric Acid SCHEMBL9936599 | 0.70 | PIM1 (0.59) | PIM1TTKPIM2 | |
| SCHEMBL10218687 | 0.70 | PIM1 (0.49) | PIM1TTKPIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614065-B1 | SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2017-04-19 | — | — | EP | disclosed |