Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 15/20 | 0.63 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10306615 | 1.00 | BCHE (0.63) | BCHETHRATHRBRARBPLK1 | |
| SCHEMBL14264266 | 1.00 | BCHE (0.63) | BCHETHRATHRBRARBPLK1 | |
| SCHEMBL15764102 | 1.00 | BCHE (0.63) | BCHETHRATHRBRARBPLK1 | |
| SCHEMBL21704943 | 1.00 | BCHE (0.63) | BCHETHRATHRBRARBPLK1 | |
| SCHEMBL18232050 | 0.91 | BCHE (0.55) | BCHETHRATHRBTP53 | |
| SCHEMBL14749470 | 0.90 | BCHE (0.75) | BCHETHRATHRBRARB | |
| SCHEMBL18133142 | 0.90 | BCHE (0.75) | BCHETHRATHRBRARB | |
| SCHEMBL14767332 | 0.90 | BCHE (0.75) | BCHETHRATHRBRARB | |
| SCHEMBL1708831 | 0.88 | BCHE (0.59) | BCHETHRATHRB | |
| SCHEMBL21558911 | 0.88 | BCHE (0.54) | BCHETHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370420-B9 | PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2019-11-13 | — | — | EP | disclosed |
| EP-2370420-B1 | PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2019-05-22 | — | — | EP | disclosed |
| EP-2651913-B1 | INDENO-FUSED RING COMPOUNDS HAVING PHOTOCHROMIC PROPERTIES | TRANSITIONS OPTICAL INC (US) | 2017-04-19 | — | — | EP | disclosed |