Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ME2 | P23368 | 1/20 | 0.40 |
| ▸ | ME1 | P48163 | 1/20 | 0.40 |
| ▸ | ME3 | Q16798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708826 | 0.96 | BCHE (0.63) | BCHES1PR1THRATHRBME2 | |
| SCHEMBL18754187 | 0.88 | BCHE (0.63) | BCHETHRATHRB | |
| SCHEMBL14264266 | 0.88 | BCHE (0.63) | BCHETHRATHRB | |
| SCHEMBL21704943 | 0.88 | BCHE (0.63) | BCHETHRATHRB | |
| SCHEMBL15764102 | 0.88 | BCHE (0.63) | BCHETHRATHRB | |
| SCHEMBL10306615 | 0.88 | BCHE (0.63) | BCHETHRATHRB | |
| SCHEMBL14749470 | 0.86 | BCHE (0.75) | BCHETHRATHRBALDH1A1MAPT | |
| SCHEMBL18133142 | 0.86 | BCHE (0.75) | BCHETHRATHRBALDH1A1MAPT | |
| SCHEMBL14767332 | 0.86 | BCHE (0.75) | BCHETHRATHRBALDH1A1MAPT | |
| SCHEMBL1708823 | 0.83 | BCHE (0.51) | BCHETHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8287969-B2 | Isosorbide derivatives and liquid crystal displays comprising the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-10-16 | — | — | US | disclosed |
| US-20120086902-A1 | ISOSORBIDE DERIVATIVES AND LIQUID CRYSTAL DISPLAYS COMPRISING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120086902-A1 | ISOSORBIDE DERIVATIVES AND LIQUID CRYSTAL DISPLAYS COMPRISING THE SAME | CX3CR1, CBX3, YBX3 | BCHE 1786/4885S1PR1 3274/4885THRA 4206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.