Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 12/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29523156 | 1.00 | P2RX3 (0.52) | P2RX3HRH3KCNH2MCL1NR1H2 | |
| SCHEMBL12442648 | 1.00 | P2RX3 (0.52) | P2RX3HRH3KCNH2MCL1NR1H2 | |
| SCHEMBL18617461 | 1.00 | P2RX3 (0.52) | P2RX3HRH3KCNH2MCL1NR1H2 | |
| SCHEMBL6846802 | 0.90 | P2RX3 (0.53) | P2RX3HRH3KCNH2MCL1NR1H2 | |
| SCHEMBL6846804 | 0.90 | P2RX3 (0.53) | P2RX3HRH3KCNH2MCL1NR1H2 | |
| SCHEMBL25365111 | 0.90 | P2RX3 (0.53) | P2RX3MCL1NR1H2NR1H3 | |
| SCHEMBL23632505 | 0.89 | P2RX3 (0.51) | P2RX3HRH3KCNH2MCL1NR1H2 | |
| SCHEMBL23632277 | 0.89 | P2RX3 (0.51) | P2RX3HRH3KCNH2MCL1NR1H2 | |
| SCHEMBL23632438 | 0.89 | P2RX3 (0.51) | P2RX3HRH3KCNH2MCL1NR1H2 | |
| SCHEMBL23632270 | 0.89 | P2RX3 (0.51) | P2RX3HRH3KCNH2MCL1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534170-B1 | IAP BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2017-04-19 | — | — | EP | disclosed |