Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.33 |
| ▸ | FASN | P49327 | 6/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18756057 | 0.83 | CHRM1 (0.52) | CHRM1 | |
| SCHEMBL18725487 | 0.80 | CHRM1 (0.50) | CHRM1PDE2APDE11ASCN9A | |
| SCHEMBL21235159 | 0.79 | CHRM1 (0.48) | CHRM1PDE2APDE11A | |
| SCHEMBL18756158 | 0.79 | CHRM1 (0.48) | CHRM1PDE2APDE11A | |
| SCHEMBL21235440 | 0.73 | CHRM1 (0.48) | CHRM1 | |
| SCHEMBL18756705 | 0.72 | CHRM1 (0.48) | CHRM1PDE2APDE11A | |
| SCHEMBL18756167 | 0.72 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL21235424 | 0.72 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL18756686 | 0.72 | IDH1 (0.40) | RORC | |
| SCHEMBL21235431 | 0.71 | CHRM1 (0.36) | CHRM1PDE2APDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |
| EP-3156397-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2017-04-19 | — | — | EP | disclosed |