Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21235431 | 0.86 | CHRM1 (0.36) | CHRM1PIK3CAMTORKCNH2PDE2A | |
| SCHEMBL18725367 | 0.81 | CHRM1 (0.51) | CHRM1PDE2APDE11A | |
| SCHEMBL18756164 | 0.77 | KCNH2 (0.42) | CHRM1PIK3CAMTORKCNH2GRM2 | |
| SCHEMBL18756126 | 0.74 | GRM2 (0.42) | PIK3CAKCNH2GRM2 | |
| SCHEMBL18756162 | 0.72 | CHRM1 (0.58) | CHRM1KCNH2 | |
| SCHEMBL18756165 | 0.71 | ADORA2A (0.45) | CHRM1 | |
| SCHEMBL21235164 | 0.71 | CHRM1 (0.53) | CHRM1PDE2APDE11A | |
| SCHEMBL18725517 | 0.71 | CHRM1 (0.53) | CHRM1PDE2APDE11A | |
| SCHEMBL21235161 | 0.70 | KCNH2 (0.41) | CHRM1PIK3CAMTORKCNH2GRM2 | |
| SCHEMBL18725426 | 0.69 | CHRM1 (0.46) | CHRM1PDE2APDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2017-04-19 | — | — | EP | disclosed |