Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 17/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP10 | P09238 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725517 | 1.00 | CHRM1 (0.53) | CHRM1PDE2APDE11AMMP3MMP7 | |
| SCHEMBL18725367 | 0.90 | CHRM1 (0.51) | CHRM1PDE2APDE11A | |
| SCHEMBL18725453 | 0.87 | CHRM1 (0.60) | CHRM1 | |
| SCHEMBL18725381 | 0.86 | CHRM1 (0.63) | CHRM1PDE2APDE11A | |
| SCHEMBL18756230 | 0.86 | CHRM1 (0.46) | CHRM1PDE2APDE11A | |
| SCHEMBL18725426 | 0.86 | CHRM1 (0.46) | CHRM1PDE2APDE11A | |
| SCHEMBL21545710 | 0.85 | CHRM1 (0.47) | CHRM1PDE2APDE11AMMP3MMP7 | |
| SCHEMBL19932675 | 0.85 | CHRM1 (0.47) | CHRM1PDE2APDE11AMMP3MMP7 | |
| SCHEMBL18725487 | 0.85 | CHRM1 (0.50) | CHRM1PDE2APDE11A | |
| SCHEMBL18756217 | 0.85 | GABRA1 (0.46) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |