Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28287911 | 0.82 | TDP1 (0.40) | CASP1MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL23558913 | 0.81 | CASP1 (0.36) | CASP1MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL10049737 | 0.80 | TDP1 (0.45) | CASP1MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL9313394 | 0.79 | TDP1 (0.38) | CASP1MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL18159716 | 0.77 | TDP1 (0.39) | CASP1MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL7443991 | 0.77 | TDP1 (0.36) | MAPTALDH1A1TDP1TSHRCACNA1B | |
| SCHEMBL12307316 | 0.77 | CASP1 (0.39) | CASP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7444000 | 0.77 | TDP1 (0.36) | MAPTALDH1A1TDP1TSHRCACNA1B | |
| SCHEMBL16915198 | 0.77 | CASP1 (0.36) | CASP1MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL9314219 | 0.77 | CASP1 (0.36) | CASP1MAPTALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |