Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579598 | 0.83 | ACACB (0.41) | ACACBGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4579594 | 0.83 | ACACB (0.41) | SMN1; SMN2ACACBGAAMEN1KMT2A | |
| SCHEMBL4580072 | 0.83 | ACACB (0.41) | SMN1; SMN2ACACBGAAMEN1KMT2A | |
| SCHEMBL4580077 | 0.83 | ACACB (0.41) | ACACBGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4577431 | 0.83 | ACACB (0.41) | SMN1; SMN2ACACBGAAMEN1KMT2A | |
| SCHEMBL4577433 | 0.83 | ACACB (0.41) | ACACBGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL19090742 | 0.80 | CA12 (0.43) | MMP1MMP2ACACBGAACA12 | |
| SCHEMBL7725268 | 0.79 | MEN1 (0.43) | MMP1MMP2SMN1; SMN2ACACBCA12 | |
| SCHEMBL26343555 | 0.79 | MMP1 (0.39) | MMP1MMP2MMP3SMN1; SMN2ACACB | |
| SCHEMBL16917911 | 0.79 | MEN1 (0.40) | MMP1MMP2MMP3SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |