Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 3/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18756195 | 0.88 | CCNC (0.45) | CHRM1GRM2CSF1RTTK | |
| SCHEMBL18725466 | 0.82 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL18725465 | 0.82 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL18725468 | 0.82 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL21873398 | 0.73 | CHRM1 (0.48) | CYP11B1CYP11B2CHRM1GRM2CSF1R | |
| SCHEMBL23698889 | 0.73 | CHRM1 (0.46) | CYP11B1CYP11B2CHRM1GRM2CSF1R | |
| SCHEMBL30428197 | 0.73 | CHRM1 (0.49) | CYP11B1CYP11B2CHRM1GRM2CSF1R | |
| SCHEMBL21873365 | 0.73 | CHRM1 (0.49) | CYP11B1CYP11B2CHRM1GRM2CSF1R | |
| SCHEMBL28440183 | 0.73 | CYP11B1 (0.51) | CYP11B1CYP11B2CHRM1CSF1R | |
| SCHEMBL30452574 | 0.73 | CYP11B1 (0.51) | CYP11B1CYP11B2CHRM1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |
| EP-3156397-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2017-04-19 | — | — | EP | disclosed |