Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28440183 | 1.00 | CYP11B1 (0.51) | CYP11B1CYP11B2EGFRMAPK8KCNJ1 | |
| SCHEMBL28895642 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2KCNJ1NPC1RAB9A | |
| SCHEMBL25242176 | 0.83 | MAPK8 (0.51) | EGFRMAPK8CHRM1CLK1MKNK1 | |
| SCHEMBL17090962 | 0.79 | CYP11B1 (0.54) | CYP11B1CYP11B2KCNJ1USP30CHRM1 | |
| SCHEMBL2362506 | 0.79 | CYP11B1 (0.59) | CYP11B1CYP11B2KCNJ1FGFR3MKNK1 | |
| SCHEMBL14906787 | 0.77 | CYP11B1 (0.60) | CYP11B1CYP11B2KCNJ1NPC1RAB9A | |
| SCHEMBL17121368 | 0.77 | DYRK1A (0.48) | CYP11B1CYP11B2KCNJ1CHRM1CSF1R | |
| SCHEMBL877044 | 0.77 | MEN1 (0.47) | EGFRNPC1ALDH1A1RAB9A | |
| SCHEMBL31506073 | 0.76 | CTSV (0.49) | EGFRMAPK8CLK1 | |
| SCHEMBL1559773 | 0.76 | ABL1 (0.49) | EGFRMAPK8USP30FGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484479-B | Azacyclic compounds, pharmaceutical compositions containing the same, and methods of making and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |