Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087588 | 0.88 | TDP1 (0.52) | TDP1MEN1GAAKMT2AAPLNR | |
| SCHEMBL1620621 | 0.85 | HDAC3 (0.46) | TDP1MEN1GAAKMT2AAPLNR | |
| SCHEMBL1885244 | 0.83 | TDP1 (0.47) | TDP1MEN1GAAKMT2AAPLNR | |
| SCHEMBL27807196 | 0.81 | TDP1 (0.50) | TDP1APLNRCA1CA2CA12 | |
| SCHEMBL27647767 | 0.81 | TDP1 (0.50) | TDP1APLNRCA1CA2CA12 | |
| SCHEMBL27938329 | 0.81 | TDP1 (0.50) | TDP1APLNRCA1CA2CA12 | |
| SCHEMBL27919778 | 0.81 | TDP1 (0.50) | TDP1APLNRCA1CA2CA12 | |
| SCHEMBL27842062 | 0.81 | TDP1 (0.50) | TDP1APLNRCA1CA2CA12 | |
| SCHEMBL7192070 | 0.81 | TDP1 (0.50) | TDP1APLNRCA1CA2CA12 | |
| SCHEMBL27807201 | 0.81 | TDP1 (0.50) | TDP1APLNRCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894376-A | Aromatic amide compound, pharmaceutical composition and application thereof | 南京雷正医药科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |