Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27938329 | 1.00 | TDP1 (0.50) | TDP1HDAC1HDAC3HDAC2EPHX1 | |
| SCHEMBL27842062 | 1.00 | TDP1 (0.50) | TDP1HDAC1HDAC3HDAC2EPHX1 | |
| SCHEMBL7192070 | 1.00 | TDP1 (0.50) | TDP1HDAC1HDAC3HDAC2EPHX1 | |
| SCHEMBL27919778 | 1.00 | TDP1 (0.50) | TDP1HDAC1HDAC3HDAC2EPHX1 | |
| SCHEMBL27647767 | 1.00 | TDP1 (0.50) | TDP1HDAC1HDAC3HDAC2EPHX1 | |
| SCHEMBL27807196 | 1.00 | TDP1 (0.50) | TDP1HDAC1HDAC3HDAC2EPHX1 | |
| SCHEMBL1885244 | 0.98 | TDP1 (0.47) | TDP1HDAC1HDAC3HDAC2EPHX1 | |
| SCHEMBL1620621 | 0.93 | HDAC3 (0.46) | TDP1HDAC1HDAC3HDAC2CA12 | |
| SCHEMBL3252218 | 0.85 | CA1 (0.43) | TDP1HDAC1HDAC3HDAC2CA12 | |
| SCHEMBL7303091 | 0.84 | TDP1 (0.49) | TDP1HDAC1HDAC3HDAC2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046628-A | Alpha helix mimetics and methods relating thereto | PRISM BIOLAB CORP | 2011-05-04 | — | — | CN | disclosed |