Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526213 | 0.87 | HSP90AA1 (0.49) | TSHRGAAGFERAPOBEC3GHTT | |
| SCHEMBL30306582 | 0.87 | HSP90AA1 (0.49) | TSHRGAAGFERAPOBEC3GHTT | |
| SCHEMBL7079519 | 0.83 | MEN1 (0.58) | GAAGFERALDH1A1HSD17B10NR1H2 | |
| SCHEMBL7079521 | 0.81 | SMN1; SMN2 (0.52) | TSHRCYP2C9GAAHTTALDH1A1 | |
| SCHEMBL20865561 | 0.80 | ALDH1A1 (0.56) | GAAALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL22113057 | 0.80 | KMT2A (0.49) | GAAGFERAPOBEC3GALDH1A1NR1H2 | |
| SCHEMBL4016652 | 0.79 | MAPT (0.54) | HTTALDH1A1IDH1SMN1; SMN2MEN1 | |
| SCHEMBL18677862 | 0.78 | CA12 (0.51) | GAAALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL18757898 | 0.78 | CA12 (0.44) | ALDH1A1MEN1KMT2ACA12CA1 | |
| SCHEMBL31173043 | 0.77 | CA12 (0.52) | GAAALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066428-A1 | BRD4-KINASE INHIBITORS AS CANCER THERAPEUTICS | H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, INC. (US) | 2017-04-20 | — | — | WO | disclosed |