Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | SYK | P43405 | 4/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17563731 | 0.97 | KDM4E (0.50) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL18466757 | 0.93 | KDM4E (0.52) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL17564685 | 0.84 | KDM4E (0.59) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL17577083 | 0.84 | KMT2A (0.50) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL18466785 | 0.84 | KMT2A (0.50) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL17564312 | 0.84 | KMT2A (0.50) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL17563721 | 0.83 | LMNA (0.42) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL17564316 | 0.83 | KDM4E (0.39) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL18679859 | 0.83 | KDM4E (0.57) | KDM4EKMT2ACA12CA1CA2 | |
| SCHEMBL18680197 | 0.83 | KDM4E (0.57) | KDM4EKMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016036847-A9 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-04-20 | — | — | WO | disclosed |