Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.71 |
| ▸ | TGM2 | P21980 | 1/20 | 0.70 |
| ▸ | KRAS | P01116 | 7/20 | 0.64 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.63 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.63 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.60 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.60 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.60 |
| ▸ | HINT1 | P49773 | 1/20 | 0.59 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18741084 | 1.00 | NT5E (0.71) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL18769144 | 1.00 | NT5E (0.71) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL21171852 | 1.00 | NT5E (0.71) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL21184245 | 0.96 | TGM2 (0.66) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL21162739 | 0.96 | TGM2 (0.66) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL18769384 | 0.95 | TGM2 (0.64) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL18769147 | 0.93 | TGM2 (0.62) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL21725246 | 0.93 | TGM2 (0.65) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL8202050 | 0.91 | NT5E (0.83) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL21184319 | 0.90 | TGM2 (0.64) | NT5ETGM2KRASFUT5IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066793-A1 | MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| WO-2017066797-A1 | TRINUCLEOTIDE MRNA CAP ANALOGS | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |