SCHEMBL18759047

COc1ccc(C(O[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](n3cnc4c(=O)[nH]c(NC(=O)COc5ccc(C(C)C)cc5)nc43)O[C@@H]2COP(C)(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	TAS1R3	Q7RTX0	2/20	0.43

▸	TAS1R1	Q7RTX1	2/20	0.43

▸	TYMP	P19971	3/20	0.41

▸	IMPDH2	P12268	3/20	0.37

▸	IMPDH1	P20839	1/20	0.37

▸	FUT6	P51993	3/20	0.35

▸	KRAS	P01116	4/20	0.34

▸	HPGD	P15428	1/20	0.34

▸	NT5E	P21589	2/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21725233	0.96	TAS1R3 (0.42)	TAS1R3TAS1R1TYMPIMPDH2IMPDH1
SCHEMBL18769136	0.95	TAS1R3 (0.41)	TAS1R3TAS1R1TYMPIMPDH2IMPDH1
SCHEMBL18769139	0.86	TYMP (0.36)	TAS1R3TAS1R1TYMPHPGDALDH1A1
SCHEMBL21184283	0.86	TYMP (0.36)	TAS1R3TAS1R1TYMPHPGDALDH1A1
SCHEMBL18759035	0.86	TYMP (0.36)	TAS1R3TAS1R1TYMPHPGDALDH1A1
SCHEMBL21163079	0.86	TYMP (0.36)	TAS1R3TAS1R1TYMPHPGDALDH1A1
SCHEMBL21171618	0.86	TYMP (0.36)	TAS1R3TAS1R1TYMPHPGDALDH1A1
SCHEMBL18759043	0.86	TYMP (0.36)	TAS1R3TAS1R1TYMPHPGDALDH1A1
SCHEMBL21475702	0.82	TYMP (0.44)	TAS1R3TAS1R1TYMPIMPDH2IMPDH1
SCHEMBL25436741	0.81	TYMP (0.53)	TAS1R3TAS1R1TYMPHPGDNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017066797-A1	TRINUCLEOTIDE MRNA CAP ANALOGS	MODERNATX, INC. (US)	2017-04-20	—	—	WO	disclosed