SCHEMBL18759756

SCHEMBL18759756

CN(CCC(=O)O)C(=O)c1cc(C(=O)NCCCOCCOCCOCCCNC(=O)CCCCC2SCC3NC(=O)NC32)cc(C(=O)NCCCOCCOCCOCCCNC(=O)CCCCC2SCC3NC(=O)NC32)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 9/20 0.55
▸ F2 P00734 1/20 0.54
▸ PRSS1 P07477 1/20 0.54
▸ PRSS2 P07478 1/20 0.54
▸ PRSS3 P35030 1/20 0.54
▸ TPSAB1 Q15661 1/20 0.54
▸ TDP1 Q9NUW8 4/20 0.52
▸ PKM P14618 3/20 0.51
▸ L3MBTL3 Q96JM7 1/20 0.51
▸ MEN1 O00255 1/20 0.50
▸ ABL1 P00519 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ IDE P14735 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ RIN1 Q13671 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ NSD2 O96028 1/20 0.50
▸ NSD3 Q9BZ95 1/20 0.50
▸ HSP90AB1 P08238 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18759806 0.93 PRSS1 (0.54) FOLH1F2PRSS1PRSS2PRSS3
SCHEMBL18760076 0.91 FOLH1 (0.53) FOLH1F2PRSS1PRSS2PRSS3
SCHEMBL10036981 0.88 F2 (0.62) FOLH1F2PRSS1PRSS2PRSS3
SCHEMBL18759554 0.86 F2 (0.62) FOLH1F2PRSS1PRSS2PRSS3
SCHEMBL10002270 0.86 F2 (0.58) FOLH1F2PRSS1PRSS2PRSS3
SCHEMBL10002255 0.86 F2 (0.59) FOLH1F2PRSS1PRSS2PRSS3
SCHEMBL18759549 0.86 TDP1 (0.57) FOLH1F2PRSS1PRSS2PRSS3
SCHEMBL18759856 0.85 PKM (0.57) FOLH1F2PRSS1PRSS2PRSS3
SCHEMBL18759543 0.85 TDP1 (0.58) FOLH1F2PRSS1PRSS2PRSS3
SCHEMBL18759670 0.84 PKM (0.52) FOLH1F2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10174363-B2 Methods for nucleic acid sequencing Quantum-Si Incorporated (US) 2019-01-08 — — US disclosed
US-20170107562-A1 METHODS FOR NUCLEIC ACID SEQUENCING Quantum-Si Incorporated (US) 2017-04-20 — — US disclosed
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