Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.74 |
| ▸ | RAB9A | P51151 | 8/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | G6PD | P11413 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385524 | 0.82 | TP53 (0.61) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL17318577 | 0.79 | KDM4E (0.73) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL11387946 | 0.78 | RXFP1 (0.58) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL17318653 | 0.76 | SMN1; SMN2 (0.75) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL28791199 | 0.75 | KMT2A (0.68) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL29538313 | 0.75 | KMT2A (0.68) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL17318701 | 0.75 | CSNK2A2 (0.80) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL6848692 | 0.74 | KMT2A (0.70) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL4954631 | 0.74 | NPC1 (0.71) | NPC1RAB9AKMT2ARXFP1MEN1 | |
| SCHEMBL17725788 | 0.74 | KDM4E (0.71) | NPC1RAB9AKMT2ARXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114060-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114060-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | ZC3HAV1, MAVS, EIF2AK2 | NPC1 237/4885RAB9A 1296/4885KMT2A 2451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.