SCHEMBL187632

SCHEMBL187632

CCCCO[Si](C)OCCCC

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
ADRB3 P13945 1/20 0.43
TSHR P16473 5/20 0.38
CYP3A4 P08684 2/20 0.38
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.33
HPGD P15428 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339180 0.78 ADRB2 (0.45) ADRB2ADRB1ADRB3TSHRCYP3A4
Hydrochloric Acid SCHEMBL9709358 0.75 ADRB2 (0.43) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL2141329 0.73 ADRB2 (0.41) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL21812049 0.73 ADRB2 (0.41) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL3673994 0.73 ADRB2 (0.41) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL17385975 0.73
SCHEMBL76345 0.73 CYP3A4 (0.42) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL23365088 0.71 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL23365075 0.71 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL3752170 0.71 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220403056-A1 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2022-12-22 US disclosed
EP-4058487-A2 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2022-09-21 EP disclosed
WO-2021097455-A2 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2021-05-20 WO disclosed
WO-2021045136-A1 WATER-SOLUBLE (METH)ACRYLIC RESIN AND USE THEREOF 株式会社カネカ 2021-03-11 WO disclosed
EP-2907856-B1 WATER-BASED PRIMER COMPOSITION YOKOHAMA RUBBER CO LTD (JP) 2019-05-01 EP disclosed
US-9624396-B2 Water-based primer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-04-18 US disclosed
CN-105189585-A Acrylic emulsion and water-based primer for sealing material and composition using same YOKOHAMA RUBBER CO LTD 2015-12-23 CN disclosed
US-20150252211-A1 WATER-BASED PRIMER COMPOSITION SIKA TECHNOLOGY AG (CH) 2015-09-10 US disclosed
EP-2907856-A1 WATER-BASED PRIMER COMPOSITION The Yokohama Rubber Co., Ltd. (JP) 2015-08-19 EP disclosed
CN-104718261-A Water-based primer composition YOKOHAMA RUBBER CO LTD 2015-06-17 CN disclosed
CN-1688641-A Method for producing scratch-resistant coating systems BAYER MATERIALSCIENCE AG (DE) 2005-10-26 CN disclosed
US-20050004318-A1 Curable composition OHSHIRO NOBUAKI (JP) 2005-01-06 US disclosed
EP-1452550-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-09-01 EP disclosed
CN-1524116-A Self-reactive/curable water-based solid adhesive and method of bonding with the self-reactive/curable water-based solid adhesive ����ϣ��ʽ���� 2004-08-25 CN disclosed
US-20040147674-A1 Thermoplastic resin composition KANEKA CORPORATION (JP) 2004-07-29 US disclosed
US-20040132864-A1 Self-reactive/curable water-based solid adhesive and method of bonding with the self-reactive/curable water-based solid adhesive KONISHI CO., LTD. (JP) 2004-07-08 US disclosed
EP-1431366-A1 SELF−REACTIVE/CURABLE WATER−BASED SOLID ADHESIVE AND METHOD OF BONDING WITH THE SELF−REACTIVE/CURABLE WATER−BASED SOLID ADHESIVE KONISHI CO., LTD. (JP) 2004-06-23 EP disclosed
EP-1398353-A1 THERMOPLASTIC RESIN COMPOSITION Kaneka Corporation (JP) 2004-03-17 EP disclosed
US-5068304-A Hydrolyzable silyl group containing polyether compound as a curable component joined by urethane groups capable of forming a rubber like substance ASAHI GLASS COMPANY, LTD. (JP) 1991-11-26 US disclosed
EP-0372561-A2 Moisture-curable resin composition ASAHI GLASS COMPANY LTD. (JP) 1990-06-13 EP disclosed