Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | PLG | P00747 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.94 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.94 |
| ▸ | BLM | P54132 | 2/20 | 0.89 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.89 |
| ▸ | TSHR | P16473 | 6/20 | 0.78 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.78 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.78 |
| ▸ | GABRP | O00591 | 1/20 | 0.78 |
| ▸ | GABRD | O14764 | 1/20 | 0.78 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 12-Aminododecanoic Acid SCHEMBL1235115 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Adipic Acid SCHEMBL258770 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| SCHEMBL2230318 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| SCHEMBL332272 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| SCHEMBL472263 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Sebacic Acid SCHEMBL5378952 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Aminocaproic Acid SCHEMBL21141584 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| 12-Aminododecanoic Acid SCHEMBL20767098 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Pimelic Acid SCHEMBL21465298 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| SCHEMBL188819 | 1.00 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889878-B1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2002-09-04 | — | — | EP | claimed |
| US-4085130-A | MOLECULAR SIEVES AND ALKALINE EARTH SILICATES AS CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1978-04-18 | — | — | US | claimed |
| CN-114763369-A | Aliphatic peptide chain and Fab-aliphatic chain conjugate | 正大天晴药业集团股份有限公司 | 2022-07-19 | — | — | CN | disclosed |
| EP-3842178-A1 | BRAZING MATERIAL, BRAZING MEMBER, HEAT EXCHANGER, AND MANUFACTURING METHOD OF BRAZING MEMBER | Harima Chemicals, Incorporated (JP) | 2021-06-30 | — | — | EP | disclosed |
| CN-113056524-A | Coloring composition | 住友化学株式会社 | 2021-06-29 | — | — | CN | disclosed |
| US-20210187672-A1 | BRAZING MATERIAL, BRAZING MEMBER, HEAT EXCHANGER, AND PRODUCING METHOD OF BRAZING MEMBER | HARIMA CHEMICALS, INCORPORATED (JP) | 2021-06-24 | — | — | US | disclosed |
| CN-112996860-A | Coloring composition | 住友化学株式会社 | 2021-06-18 | — | — | CN | disclosed |
| US-9463262-B2 | Cell adhesive material for biological tissue | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20130289254-A1 | CELL ADHESIVE MATERIAL FOR BIOLOGICAL TISSUE | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2013-10-31 | — | — | US | disclosed |
| EP-2636415-A1 | CELL ADHESIVE MATERIAL FOR BIOLOGICAL TISSUE | Sanyo Chemical Industries, Ltd. (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-20110105417-A1 | Drug Conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-05-05 | — | — | US | disclosed |
| US-5360914-A | Intermediates for superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| US-5238837-A | Antiinflammatory agents, antiulcer agents | KURARAY CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0507348-A2 | Superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4085130-A | MOLECULAR SIEVES AND ALKALINE EARTH SILICATES AS CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4069277-A | ZINC DIHYDROCARBYL DITHIOPHOSPHINATE | PHILLIPS FIBERS CORPORATION (US) | 1978-01-17 | — | — | US | disclosed |
| US-4059653-A | ZINC ALKYL SULFINATE | PHILLIPS PETROLEUM COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | ABCB1, SLCO2B1, ABCG2 | LMNA 2282/4885KMT2A 3940/4885ALDH1A1 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.