Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707369 | 0.83 | ALDH1A1 (0.55) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| Potassium SCHEMBL30621340 | 0.83 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL29364103 | 0.82 | ALDH1A1 (0.67) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL109921 | 0.82 | ALDH1A1 (0.67) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL30621339 | 0.81 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL29851227 | 0.81 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL3859151 | 0.81 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL30621342 | 0.81 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| Hydrochloric Acid SCHEMBL4359705 | 0.81 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL28420832 | 0.81 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430463-B | Improved synthesis of honokiol | 高露洁-棕榄公司 | 2021-01-29 | — | — | CN | disclosed |
| EP-3364957-B1 | IMPROVED SYNTHESIS OF HONOKIOL | COLGATE PALMOLIVE CO (US) | 2020-12-09 | — | — | EP | disclosed |
| EP-3364957-A1 | IMPROVED SYNTHESIS OF HONOKIOL | Colgate-Palmolive Company (US) | 2018-08-29 | — | — | EP | disclosed |
| US-10053406-B2 | Synthesis of honokiol | COLGATE-PALMOLIVE COMPANY (US) | 2018-08-21 | — | — | US | disclosed |
| US-20170113989-A1 | SYNTHESIS OF HONOKIOL | COLGATE-PALMOLIVE COMPANY | 2017-04-27 | — | — | US | disclosed |
| WO-2017070568-A1 | IMPROVED SYNTHESIS OF HONOKIOL | COLGATE-PALMOLIVE COMPANY (US) | 2017-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170113989-A1 | SYNTHESIS OF HONOKIOL | UGT2B7, UGT1A7, DHCR7 | ALDH1A1 276/4885ALOX15 323/4885HSD17B10 377/4885 |
| US-10053406-B2 | Synthesis of honokiol | UGT2B7, UGT1A7, DHCR7 | ALDH1A1 276/4885ALOX15 323/4885HSD17B10 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.