Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18764639 | 0.80 | SMN1; SMN2 (0.41) | CA9CA12HTTSMN1; SMN2 | |
| SCHEMBL30583096 | 0.70 | MAOB (0.62) | CA9CA1CA2PARP1MAOA | |
| SCHEMBL49433 | 0.70 | MAOB (0.62) | CA9CA1CA2PARP1MAOA | |
| SCHEMBL28158901 | 0.68 | MAOB (0.52) | CA9CA1CA2MAOAMAOB | |
| SCHEMBL9719335 | 0.68 | MAOB (0.60) | CA9CA1CA2PARP1MAOA | |
| Hydrochloric Acid SCHEMBL10936113 | 0.68 | MAOB (0.64) | CA9CA1CA2PARP1MAOA | |
| Hydrochloric Acid SCHEMBL8644377 | 0.68 | MAOB (0.64) | CA9CA1CA2PARP1MAOA | |
| SCHEMBL9719373 | 0.66 | CA1 (0.62) | CA9CA1CA2PARP1MAOA | |
| SCHEMBL29569802 | 0.66 | CA1 (0.62) | CA9CA1CA2PARP1MAOA | |
| SCHEMBL3482569 | 0.66 | CA1 (0.62) | CA9CA1CA2PARP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365337-A1 | PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | Selvita S.A. (PL) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017068064-A1 | PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | SELVITA S.A. (PL) | 2017-04-27 | — | — | WO | disclosed |