Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580459 | 0.82 | DAO (0.39) | HCAR1DAOCA12CA9TYMP | |
| SCHEMBL18764630 | 0.80 | CA9 (0.41) | SMN1; SMN2CA12CA9HTT | |
| SCHEMBL6205311 | 0.76 | HNF4A (0.45) | SMN1; SMN2HCAR1ALDH1A1PTPN1KDM4E | |
| SCHEMBL27849224 | 0.71 | CALM1 (0.44) | LTB4RCALM1CTRCKMT2AMEN1 | |
| SCHEMBL27711723 | 0.69 | TYMP (0.51) | DAOTYMPKMT2AALDH1A1HPGD | |
| SCHEMBL28820480 | 0.68 | ALDH1A1 (0.51) | SMN1; SMN2LTB4RKMT2AMEN1ALDH1A1 | |
| SCHEMBL28747205 | 0.67 | SMN1; SMN2 (0.53) | SMN1; SMN2CALM1DAOTYMPTAAR1 | |
| Diphenylmethane SCHEMBL10711103 | 0.66 | CALM1 (0.63) | SMN1; SMN2CALM1DAOTYMPKMT2A | |
| SCHEMBL28853115 | 0.65 | CALM1 (0.52) | LTB4RCALM1DAOTYMPKMT2A | |
| SCHEMBL14446906 | 0.64 | DAO (0.47) | SMN1; SMN2LTB4RCALM1DAOTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365337-A1 | PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | Selvita S.A. (PL) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017068064-A1 | PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | SELVITA S.A. (PL) | 2017-04-27 | — | — | WO | disclosed |
| CN-100334085-C | Quinuclidine compound and medicine containing the same as active ingredient | EISAI R & D CO LTD (JP) | 2007-08-29 | — | — | CN | disclosed |
| CN-1377349-A | Quinuclidine compound and medicine containing the same as active ingredient | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |