SCHEMBL18768271

SCHEMBL18768271

CC(=O)OC1CC2CC1C1CCC(OC(=O)C(C)(C)C)C21

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 5/20 0.34
CHRM1 P11229 3/20 0.34
MEN1 O00255 1/20 0.34
CYP2D6 P10635 1/20 0.34
KMT2A Q03164 1/20 0.34
CHRM4 P08173 2/20 0.32
CHRM3 P20309 2/20 0.32
APOBEC3A P31941 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18768268 0.89 CHRM2 (0.35) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL15113771 0.86 CHRM2 (0.31) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL20161030 0.84 GSR (0.30) CHRM1
SCHEMBL18633945 0.80 GSR (0.32) CHRM2CHRM1CYP2D6CHRM4CHRM3
SCHEMBL19151708 0.79
SCHEMBL18758044 0.79 CHRM2 (0.34) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL75220 0.79 CHRM2 (0.34) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL19829285 0.78 CHRM2 (0.38) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL23974120 0.78 CHRM2 (0.33) CHRM2CHRM1MEN1CYP2D6KMT2A
SCHEMBL25618017 0.78 CHRM2 (0.33) CHRM2CHRM1CHRM4CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024435-A1 RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-25 US disclosed
US-20170108775-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-20 US disclosed